- Antibody Type:Primary
- Antigen Name:Estrogen Receptor alpha + beta
- Antigen Symbol:Estrogen Receptor alpha + beta
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Cross Adsorption:No
- Form:liquid
- Gene ID:2099, 2100
- Antigen Synonyms:Estradiol receptor|Nuclear receptor subfamily 3 group A member 2|Estrogen Receptor alpha/beta|ER|OTTHUMP00000017719|Era|ESR BETA|Estrogen receptor alpha|ER-beta|Estrogen receptor 2 ER beta|ERalpha|Estr|augmented response of|Estradiol Receptor alpha|Estrogen Receptor 2|ESRA|OTTHUMP00000017718|NR3A1|ESR2|Estrogen receptor|Atherosclerosis|susceptibility to|ER-alpha|ER Beta|ESR|ESR1|HDL cholesterol|to hormone replacement|Nuclear receptor subfamily 3 group A member 1|Estrogen Receptor 1|ESRB|included|Erb|Estradiol Receptor beta|NR3A2|Estra|Estrogen resistance|Estrogen receptor 1 alpha|ER Alpha|Estrogen receptor beta 4|Erb2|ESTRB|DKFZp686N23123|ER[a]|ESR1_HUMAN|Myocardial infarction|ER[b]|ERbeta|RNESTROR.
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage Temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10232-596
- Supplier no.:BS-0174R
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: Estrogen Receptor alpha + beta
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat