Specifications
- Antibody Type:Primary
- Antigen Name:Adaptor-Related Protein Complex 2, Mu 1 Subunit
- Antigen Symbol:AP2M1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Chicken
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Epitope:C-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:1173
- Antigen Synonyms:mu2|CLAPM1|AP50
- Concentration:1.0 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:AP2M1 Antibody was produced in chicken by repeated immunizations with a peptide near the c-terminus of human AP2M1.
- Purification:Anti-AP2M1 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with AP2M1 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with AP2M1 from other sources has not been determined.
- Cat. No.:10800-040
- Supplier no.:600-901-G75
Specifications
About this item
AP2M1 antibody detects human AP2M1. The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist. Anti-AP2M1 antibodies are ideal for investigators involved in infectious disease and enzyme research.
Recommended Dilutions: Western Blot: 1-2 ug/mL; contains 0.01% (w/v) Sodium Azide
Type: Primary
Antigen: AP2M1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Chicken
Isotype:
Reactivity: Human, Mouse, Rat