Specifications
- Antibody Type:Primary
- Antigen Name:CAP-GLY Domain Containing linker protein 1
- Antigen Symbol:CLIP1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Epitope:C-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:6249
- Antigen Synonyms:CLIP170|CLIP-170|CLIP|RSN|CYLN1
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-CLIP170 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the C-terminus of human CLIP170.
- Purification:Anti-CLIP170 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CLIP170 from other sources has not been determined.
- Cat. No.:10800-838
- Supplier no.:600-401-AL8
Specifications
About this item
CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.
Recommended Dilutions: ELISA: 1:5000-1:10000; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 0.5-1 ?g/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: CLIP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: