- Antibody Type:Primary
- Antigen Name:nuclear cap binding protein subunit 1, 80kDa
- Antigen Symbol:NCBP1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.02 mg
- Cross Adsorption:No
- Form:Liquid
- Gene ID:Q09161
- Antigen Synonyms:NCBP1
- Storage Buffer:NCBP1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular Weight:Predicted: 87 kDa Observed: 87 kDa
- Storage Temperature:NCBP1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1. The immunogen is located within amino acids 420 - 470 of NCBP1.
- Tested Applications:Immunocytochemistry
- Purification:NCBP1 Antibody is affinity chromatography purified via peptide column.
- Cat. No.:10752-000
- Supplier no.:7395_S
NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation.
Type: Primary
Antigen: NCBP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat