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Anti-ZBTB5 Rabbit Polyclonal Antibody
Anti-ZBTB5 Rabbit Polyclonal Antibody
Catalog # 10751-196
Supplier:  Prosci
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Anti-ZBTB5 Rabbit Polyclonal Antibody
Catalog # 10751-196
Supplier:  Prosci
Supplier Number:  6123_S

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    zinc finger and BTB domain containing 5
  • Antigen Symbol:
    ZBTB5
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    0.02 mg
  • Cross Adsorption:
    No
  • Form:
    Liquid
  • Gene ID:
    O15062
  • Antigen Synonyms:
    ZBTB5
  • Storage Buffer:
    ZBTB5 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Storage Temperature:
    ZBTB5 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    ZBTB5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6. The immunogen is located within the last 50 amino acids of ZBTB5.
  • Purification:
    ZBTB5 Antibody is affinity chromatography purified via peptide column.
  • Cat. No.:
    10751-196
  • Supplier no.:
    6123_S

Specifications

About this item

ZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.

Type: Primary
Antigen: ZBTB5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat