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Specifications
- Protein/Peptide Type:Recombinant
- Source:HEK293 cells
- Species:Human
- Size:0.02 mg
- Environmentally Preferable:
- Tag sequence:His Tag
- Protein Synonyms:CD122|P70-75|IL2RB|RP5-1170K4.6
- Protein/Peptide Name:IL2RB
- Purity:>90% as determined by SDS-PAGE.
- Molecular Weight:25.4 kDa
- Formulation:Lyophilized, PBS, pH7.4
- Tested Applications:Western Blot
- Cat. No.:10797-138
- Supplier no.:96-097
Specifications
About this item
Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - ? (CD25), ? (CD122) and ? (CD132) - non-covalently associating. The ? and ? chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the ?-chain, along with the ? subunit.
CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.