Specifications
- Antibody Type:Primary
- Antigen Symbol:CHOP
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:150 µL
- Storage Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. No.:10084-730
- Supplier no.:15204-1-AP
Specifications
About this item
CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma. The observed molecular weight of CHOP is about 30 kDa.
Western Blot: RAW264.7 Cells, 1:500-1:5000; IHC: Human cervical cancer Tissue, 1:20-1:200; FC: HeLa Cells, N/A
Type: Primary
Antigen: CHOP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: