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Specifications
- Antibody Type:Primary
- Antigen Name:Early growth response protein 2
- Antigen Symbol:EGR2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:150 µL
- Antigen Synonyms:KROX20|Drosophila|homolog (early growth response-2)|KROX-20|Drosophila) |early growth response 2 (Krox-20 homolog|DKFZp686J1957|CMT4E|Krox-20 homolog|OTTHUMP00000062133 |CMT1D|EGR2|FLJ14547|early growth response 2 protein
- Storage Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. No.:10086-314
- Supplier no.:13491-1-AP
Specifications
About this item
Egr2 belongs to the Egr family that binds to DNA through highly conserved zinc finger domains and has a pivotal role in hindbrain development and myelination of the peripheral nervous system, development of T and/or B cells . It has been demonstrated that Egr2 is induced early upon TCR engagement in a NFAT-dependent manner, and that overexpression of Egr2 inhibits T cell activation. Overexpressing Egr2 shows an upregulation of E3-ligase Cbl-band reduced production of interleukin-2 (IL-2), suggesting that Egr2 is important for the maintenance of T cell tolerance by negatively regulating T cell activation.
Western Blot: Mouse Brain Tissue, 1:500-1:5000
Type: Primary
Antigen: EGR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Supplier: VWR International
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Supplier: Decon Labs
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