- Antibody Type:Primary
- Antigen Name:Cut-like homeobox 1
- Antigen Symbol:CUX1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:150 µL
- Antigen Synonyms:CDP/Cut|CUTL1|p75|CASP|p200|CUX|p100|GOLIM6|p110|Nbla10317|COY1|CDP|Clox|CDP1|Cux/CDP
- Storage Buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. No.:10085-362
- Supplier no.:11733-1-AP
CUX1 is a transcription factors that regulates a large number of genes and microRNAs involved in multiple cellular processes, such as DNA replication, progression into S phase and later, the spindle assembly checkpoint that controls progression through mitosis. CUX1 acts by preventing binding of positively-acting CCAAT factors to promoters to mediated its gene reperssion. Also it's a component of nf-munr repressor, and binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. It can represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer
Western Blot: Human Brain Tissue, 1:1000-1:10000; IF: HepG2 Cells, 1:10-1:100
Type: Primary
Antigen: CUX1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: