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Specifications
- Antibody Type:Primary
- Antigen Symbol:FUS/TLS
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:150 µL
- Environmentally Preferable:
- Storage Buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. No.:10087-186
- Supplier no.:11570-1-AP
Specifications
About this item
FUS (also named TLS and POMp75) belongs to the RRM TET family. FUS may play a role in the maintenance of genomic integrity; it binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS is also an RNA-binding protein, and its links to neurodegenerative disease proffer the intriguing possibility that altered RNA metabolism or RNA processing may underlie or contribute to neuron degeneration. FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) and is implicated in certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementias (FTDs) such as frontotemporal lobar dementia with ubiquitin inclusions (FTLD-U). This antibody is a rabbit polyclonal antibody raised against an internal region of human FUS.
Western Blot: HEK-293 Cells, 1:1000-1:10000; IHC: Human ovary tumor Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP:K-562 Cells, 1:500-1:5000; FC: HeLa Cells, N/A
Type: Primary
Antigen: FUS/TLS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat