Specifications
- Antibody Type:Primary
- Antigen Name:fibulin 5
- Antigen Symbol:FBLN5
- Clonality:Monoclonal
- Clone:3F10A5 / 3F8A12
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG1
- Reactivity:Human
- Western Blot:Yes
- Size:0.1 mL
- Gene ID:Q9UBX5
- Antigen Synonyms:FBLN5
- Storage Buffer:Ascitic fluid containing 0.03% sodium azide.
- Storage Temperature:Fibulin 5 monoclonal antibody can be stored at –20 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping Temperature:4 °C
- Immunogen:Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3).
- Cat. No.:10070-564
- Supplier no.:32-155
Specifications
About this item
Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.
Western Blot:1:500 - 1:2000
IHC(P):1:500 - 1:2000
IHC(F):1:500 - 1:2000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: FBLN5
Clonality: Monoclonal
Clone: 3F10A5 / 3F8A12
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human