For exceptionally high resolution and efficiency anion-exchange separation of protein variants, use Thermo Scientific™ ProPac SAX and WAX strong and weak anion-exchange columns.

Based on a nonporous 10 µm core particle that provides pressure stability, these columns can resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer prevents unwanted secondary interactions. The grafted anion-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.