Nanoflow LC-MS utilizes very narrow fused silica columns and as a result, even the slightest inconsistency in column connection can result in leaks and dead volumes are a frequent source of poor data, causing unstable spray and a significant loss in performance.

Trouble-shooting connection issues can be difficult and time consuming, even for experts. Thermo Scientific EASY-Spray Columns address the aforementioned issue by incorporating high-performance nanobore columns and integrating them within a radical new design. Packed with either C18 for peptide separations or with selected wide pore phases and monoliths for the separation of intact proteins,e.g. top-down proteomics or the structural identification of biotherapeutics, the 'plug and spray' approach delivers state of the art performance in a simple to use format, making research routine.

Nano columns packed with core-enhanced Accucore C4, for top-down proteomics.