Aurion Blocking Solutions, Electron Microscopy Sciences

Aurion blocking solutions effectively block sticky surfaces by multi-point hydrophobic and charge-based interactions. The blocking solutions are specifically designed to meet the characteristics of each type of secondary conjugate.

Prevent immunoreagents from binding non-specifically to specimens with sticky surface properties

The signal-to-noise ratio determines the quality of any detection experiment. This ratio is in principle determined by the characteristics of specimen and detection reagents. With adequate blocking and incubation media, background reactions are minimized whereas specific reactions are not hampered.

Procedures to eliminate background comprise three main steps. They are, to suppress residual aldehyde activity, to saturate multipoint hydrophobic moieties and positive charges with high molecular weight compounds such as those present in the AURION blocking solutions. These steps should be balanced for optimum results.

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