Anti-AXIN1 Rabbit Polyclonal Antibody
Catalog # 89417-632
Supplier: Prosci
Specifications
- Antibody Type:Primary
- Antigen Name:axin 1
- Antigen Symbol:AXIN1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Form:Liquid
- Gene ID:O15169
- Antigen Synonyms:AXIN1
- Storage Buffer:AXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Temperature:AXIN1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:AXIN1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1. The immunogen is located within amino acids 620 - 670 of AXIN1.
- Tested Applications:E, WB, IF
- Purification:AXIN1 Antibody is affinity chromatography purified via peptide column.
- Cat. No.:89417-632
- Supplier no.:6005
Specifications
About this item
AXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
Type: Primary
Antigen: AXIN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat