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Anti-AXIN1 Rabbit Polyclonal Antibody
Anti-AXIN1 Rabbit Polyclonal Antibody
Catalog # 89417-632
Supplier:  Prosci
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Anti-AXIN1 Rabbit Polyclonal Antibody
Catalog # 89417-632
Supplier:  Prosci
Supplier Number:  6005

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    axin 1
  • Antigen Symbol:
    AXIN1
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    0.1 mg
  • Form:
    Liquid
  • Gene ID:
    O15169
  • Antigen Synonyms:
    AXIN1
  • Storage Buffer:
    AXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Storage Temperature:
    AXIN1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    AXIN1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1. The immunogen is located within amino acids 620 - 670 of AXIN1.
  • Tested Applications:
    E, WB, IF
  • Purification:
    AXIN1 Antibody is affinity chromatography purified via peptide column.
  • Cat. No.:
    89417-632
  • Supplier no.:
    6005

Specifications

About this item

AXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.

Type: Primary
Antigen: AXIN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat