Octyl Sepharose™ 4 Fast Flow resin is based on cross-linked 4% agarose. The aliphatic ligand is immobilised to the base matrix with an ether linkage. The ligand contains no charged groups, making true hydrophobic interaction chromatography possible, without interfering ionic effects.

• Aliphatic HIC media based on Sepharose Fast Flow base matrix derivatised via uncharged, chemically-stable ether linkages
• Optimised for the separation of larger proteins in capture and intermediate purification steps
• Bioprocess medium supported for industrial applications and well established in approved processes

This resin is based on cross-linked 4% agarose. The aliphatic ligand is immobilized to the base matrix with an ether linkage. The ligand contains no charged groups, making true hydrophobic interaction chromatography possible, without interfering ionic effects. Octyl Sepharose 4 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Octyl Sepharose 4 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support.

The octyl derivative adds a different and complementary selectivity to the Sepharose Fast Flow HIC product family. Optimized for the separation of larger proteins in capture and intermediate purification steps. BioProcess medium supported for industrial applications and well established in approved processes. Octyl Sepharose 4 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades.