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- Conjugation:Unconjugated
- Protein/Peptide Type:Recombinant
- Source:CHO cells
- Species:Human
- Size:50 µg
- Storage Conditions:–20 °C
- Endotoxin Content:<0.06EU/µg
- Biological Activity:Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Gene ID:NP_003985.2
- Protein Synonyms:c-Kit Ligand|Mast Cell Grow Factor|Stem Cell Factor|MGF|Kit Ligand
- Protein/Peptide Name:SCF
- Purity:98%
- Endotoxin Level:Low
- Formulation:Lyophilized from 0.2µm-filtered solution in PBS.
- Shipping Temperature:-20 °C, Blue Ice
- Cat. No.:102511-364
- Supplier no.:HF220SCFC050
Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.