Mouse Recombinant IL6 (from CHO Cells)

Supplier: Adipogen

Supplier: Adipogen

About this item

Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.

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Specifications

Conjugation:
Unconjugated
Protein Function:
Interleukins
Protein/Peptide Type:
Recombinant
Source:
CHO cells
Species:
Mouse
Storage Conditions:
–20 °C
Endotoxin Content:
<0.06EU/µg
Biological Activity:
Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Gene ID:
NP_112445.1
Protein Synonyms:
Interleukin-6|B Cell Hybridoma Growth Factor|Interleukin HP-1
Protein/Peptide Name:
IL6
Purity:
98%
Endotoxin Level:
Low
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS.
Shipping Temperature:
-20 °C, Blue Ice