Mouse Recombinant IL4 (from CHO Cells)

Supplier: Adipogen

Supplier: Adipogen

About this item

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.

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Specifications

Conjugation:
Unconjugated
Protein Function:
Interleukins
Protein/Peptide Type:
Recombinant
Source:
CHO cells
Species:
Mouse
Storage Conditions:
–20 °C
Endotoxin Content:
<0.06EU/µg
Biological Activity:
Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Gene ID:
NP_067258.1
Protein Synonyms:
B Cell Stimulatory Factor 1|BSF-1|Interleukin-4
Protein/Peptide Name:
IL4
Purity:
98%
Endotoxin Level:
Low
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS.
Shipping Temperature:
-20 °C, Blue Ice