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- Assay Type:Sandwich
- Primary antibody reactivity:Human
- Target protein:RELM-β
- Description:RELM-beta (human) Matched Pair Detection Set
- Size:1 Set
- Storage Conditions:-20°C (long term); +4°C (short term)
- Sample Type:Serum
- Cross Reactivity:Does not cross-react with human adiponectin, mouse adiponectin, human RBP4, human Nampt, human vaspin, human GPX3, human ANGPTL3, human progranulin, human leptin, human resistin, human IL-33, human sirtuin 1, human clusterin, mouse resistin, human FABP4.
- Detection Method:Colorimetric
- Shelf Life:Stable for at least 6 months after receipt when stored at +4°C.
- Detection Range:0.016 to 1ng/ml
- Sensitivity:10 pg/ml
- Cat. No.:102515-632
- Supplier no.:AG46A0001KI01
- No. of tests:Reagents for 5× 96-well plates
RELM-beta is a 19kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel
RELM-beta has been suggested to play a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELM-beta is highly homologous to that of the adipose-derived cytokine resistin. The specific and sensitive RELM-beta Matched Pair Detection Set might detect RELM-beta in serum of gut-inflamed patients (e.g. inflammatory bowel diseases, Crohn disease and ulcerative colitis). Natural levels of RELM-beta were seen in stool, but were not detectable in the serum or other cell culture models of healthy human patients. Further testing are ongoing.