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- Conjugation:ATTO 647N
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:100 tests
- Storage Conditions:+4 °C
- Gene ID:P08758
- Protein Synonyms:Endonexin II|Calphobindin I|Placental Anticoagulant Protein I|Vascular Anticoagulant-alpha|Lipocortin V|Annexin A5
- Protein/Peptide Name:Annexin
- Purity:95%
- Molecular Weight:~52kDa (SDS-PAGE)
- Sequence:Recombinant human annexin V
- Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide.
- Shipping Temperature:-20 °C, Blue Ice
- Cat. No.:102511-444
- Supplier no.:40B0005TST100
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.