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Specifications
- Antibody Type:Primary
- Antigen Name:Progranulin
- Antigen Symbol:GRN
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rat
- Reactivity:Mouse
- Western Blot:Yes
- Size:100 µg
- Form:Liquid
- Gene ID:P28798
- Antigen Synonyms:PC Cell-derived Growth Factor|Proepithelin|PEPI
- Storage Buffer:0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Storage Temperature:Short term: +4 °C, Long Term: –20 °C
- Concentration:1mg/ml
- Shipping Temperature:-20° C
- Immunogen:Recombinant mouse progranulin.
- Cat. No.:102514-594
- Supplier no.:AG25A0093C100
Specifications
About this item
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Stable for at least 6 months after receipt when stored at -20°C.
Type:
Antigen: Progranulin
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rat
Isotype:
Reactivity: Mouse