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Specifications
- Antibody Type:Primary
- Antigen Name:Tribbles pseudokinase 3
- Antigen Symbol:TRB3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human
- Western Blot:Yes
- Size:100 µg
- Form:Liquid
- Gene ID:Q96RU7
- Antigen Synonyms:Tribbles Homolog 3|SINK|p65-interacting Inhibitor of NF-kappaB|Neuronal Cell death-inducible Putative Kinase
- Storage Buffer:0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Storage Temperature:Short term: +4 °C, Long Term: –20 °C
- Concentration:1mg/ml
- Shipping Temperature:-20° C
- Immunogen:Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
- Cat. No.:102514-524
- Supplier no.:AG25A0059C100
Specifications
About this item
Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPAR?, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
Type:
Antigen: TRB-3
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human