Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Antibody Type:Primary
- Antigen Name:TNF Receptor superfamily member 10b
- Antigen Symbol:TRAIL-R2
- Clonality:Monoclonal
- Clone:HS201
- Conjugation:ATTO 488
- Flow Cytometry:Yes
- ImmunoChemistry:Yes
- Isotype:IgG1
- Reactivity:Human
- Size:100 tests
- Form:Liquid
- Gene ID:O14763
- Antigen Synonyms:CD262|TRAIL Receptor 2|KILLER|TNFRSF10B|DR5
- Storage Buffer:In PBS containing 0.02% sodium azide.
- Storage Temperature:Short term: +4 °C, Long Term: –20 °C
- Concentration:1mg/ml
- Shipping Temperature:-20° C
- Immunogen:Recombinant human TRAIL-R2 (DR5).
- Tested Applications:FACS
- Cat. No.:102511-398
- Supplier no.:20B0023TDT100
Specifications
About this item
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- Purified from concentrated hybridoma tissue culture supernatant.
- Purity: >95% (SDS-PAGE)
Keep conjugated formats at +4°C.
Type:
Antigen: TRAIL-R2
Clonality: Monoclonal
Clone: HS201
Conjugation: ATTO 488
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human