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Ac-DEVD-CHO

Ac-DEVD-CHO
 
Ac-DEVD-CHO
Ac-DEVD-CHO

 

 

Caspase-3 inhibitor

Highly specific, potent and reversible inhibitor of caspase-3. Ki<1nM for purified caspase-3. IC50=0.2nM for PARP cleavage in cultured human osteosarcoma cell extracts. In contrast, the caspase-1 (ICE) specific inhibitor YVAD-CHO has a Ki=12µM for caspase-3 and IC50>10µM for PARP cleavage in osteosarcoma cell extracts. The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3.

 

 

 

  • Catalog No:
  • 89146-634
  • 89146-636
  • Protein/Peptide Name:
  • Ac-DEVD-CHO
  • AC-DEVD-CHO
  • Purity:
  • >95% (HPLC)
  • Peptide Content:
  • 70-90%.
  • Formulation:
  • Lyophilized
  • Reconstitution Instructions:
  • Add 0.2ml DMSO per 1mg peptide. Shake well until all the contents are dissolved. This furnishes a 10mM solution of this material.

 

Product Family Options

 

  • Size
     
     
  • 1 mg
       
       
    Each
    Each - $89.38
    $89.38
    Each
       $89.38
     

     : 260-030-M001
     
     
     
    Specifications
    Cat. No.
    89146-634
    Protein/Peptide Name
    Ac-DEVD-CHO
    Purity
    >95% (HPLC)
    Peptide Content
    70-90%.
    Formulation
    Lyophilized
    Reconstitution Instructions
    Add 0.2ml DMSO per 1mg peptide. Shake well until all the contents are dissolved. This furnishes a 10mM solution of this material.
  • 5 mg
       
       
    Each
    Each - $352.07
    $352.07
    Each
       $352.07
     

     : 260-030-M005
     
     
     
    Specifications
    Cat. No.
    89146-636
    Protein/Peptide Name
    AC-DEVD-CHO
    Purity
    Peptide Content
    Formulation
    Reconstitution Instructions