Ac-DEVD-CHO
Caspase-3 inhibitor
Highly specific, potent and reversible inhibitor of caspase-3. Ki<1nM for purified caspase-3. IC50=0.2nM for PARP cleavage in cultured human osteosarcoma cell extracts. In contrast, the caspase-1 (ICE) specific inhibitor YVAD-CHO has a Ki=12µM for caspase-3 and IC50>10µM for PARP cleavage in osteosarcoma cell extracts. The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3.
Caspase-3 inhibitor
Highly specific, potent and reversible inhibitor of caspase-3. Ki<1nM for purified caspase-3. IC50=0.2nM for PARP cleavage in cultured human osteosarcoma cell extracts. In contrast, the caspase-1 (ICE) specific inhibitor YVAD-CHO has a Ki=12µM for caspase-3 and IC50>10µM for PARP cleavage in osteosarcoma cell extracts. The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3.
- Catalog No:
- 89146-634
- 89146-636
- Protein/Peptide Name:
- Ac-DEVD-CHO
- AC-DEVD-CHO
- Purity:
- >95% (HPLC)
- Peptide Content:
- 70-90%.
- Formulation:
- Lyophilized
- Reconstitution Instructions:
- Add 0.2ml DMSO per 1mg peptide. Shake well until all the contents are dissolved. This furnishes a 10mM solution of this material.
Product Family Options
- Size
- : 260-030-M001
Specifications
Cat. No.89146-634Protein/Peptide NameAc-DEVD-CHOPurity>95% (HPLC)Peptide Content70-90%.FormulationLyophilizedReconstitution InstructionsAdd 0.2ml DMSO per 1mg peptide. Shake well until all the contents are dissolved. This furnishes a 10mM solution of this material. - : 260-030-M005
Specifications
Cat. No.89146-636Protein/Peptide NameAC-DEVD-CHOPurityPeptide ContentFormulationReconstitution Instructions



