Abz-Amyloid beta/A4 Protein Precursor₇₇₀ (669-674)-EDDnp Trifluoroacetate
Catalog # M-2560.0001BA
Supplier: Avantor
CAS Number:
Specifications
- CAS No.:1802078-43-8
- Size:1 mg
- Storage Conditions:–20 ± 5 °C
- MDL No.:MFCD06411971
- Protein/Peptide Name:Abz-Amyloid beta/A4 Protein Precursor₇₇₀ (669-674)-EDDnp Trifluoroacetate
- Molecular Weight:1019.10
- Sequence:Abz-Val-Lys-Met-Asp-Ala-Glu-EDDnp
- Molecular Formula:C₄₃H₆₂N₁₂O₁₅S
- Cat. No.:M-2560.0001BA
- Supplier no.:M-2560.0001
Specifications
About this item
Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It mimicks the wild-type (JMV2235) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is cleaved by BACE1, BACE2, and cathepsin D.