Mouse;Rat alpha-CGRP (8-37) Trifluoroacetate

About this item

α-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37) (H-2746). Furthermore, it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.

Specifications

CAS No.:
129121-73-9
Species:
Rat
Mouse
Storage Conditions:
–20 ± 5 °C
MDL No.:
MFCD18782272
Protein Synonyms:
Calcitonin Gene-Related Peptide I (8-37)|CGRP-I (8-37)
Protein/Peptide Name:
alpha-CGRP (8-37) Trifluoroacetate
Molecular Weight:
3127.56
Sequence:
H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH₂
Molecular Formula:
C₁₃₈H₂₂₄N₄₂O₄₁