Acetyl-(Nle⁴,Asp⁵,D-Phe⁷,Lys¹⁰)-cyclo-alpha-MSH (4-10) Amide Acetate

Melanotan II, a cyclic MSH analog, is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). Intracerebroventricular administration of MTII inhibited feeding in four different mouse models of hyperphagia. MTII is a valuable tool for the study of the agouti obesity syndrome and of the role of melanocortinergic neurons in feeding.

CAS No.:
121062-08-6
Storage Conditions:
–20 ± 5 °C
MDL No.:
MFCD11045941
Protein Synonyms:
Melanotan II|MTII|Bremelanotide amide
Protein/Peptide Name:
Acetyl-(Nle⁴,Asp⁵,D-Phe⁷,Lys¹⁰)-cyclo-alpha-MSH (4-10) amide Acetate
Molecular Weight:
1024.19
Sequence:
Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys-NH₂)
Molecular Formula:
C₅₀H₆₉N₁₅O₉