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Anti-SIN3B Rabbit Polyclonal Antibody
Anti-SIN3B Rabbit Polyclonal Antibody
Catalog # 89358-612
Supplier:  Genetex
Anti-SIN3B Rabbit Polyclonal Antibody
Catalog # 89358-612
Supplier:  Genetex
Supplier Number:  GTX116326

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    SIN3 transcription Regulator Family member B
  • Antigen Symbol:
    SIN3B
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • ImmunoPrecipitation:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    100 μl
  • Gene ID:
    23309
  • Antigen Synonyms:
    SIN3 homolog B transcription regulator|Transcriptional corepressor Sin3b|SIN3B_HUMAN.
  • Storage Buffer:
    0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Molecular Weight:
    40 kDa
  • Storage Temperature:
    Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid multiple freeze-thaw cycles.
  • Concentration:
    0.96 mg/ml
  • Immunogen:
    Recombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
  • Tested Applications:
    ICC/IF, IHC-P, WB
  • Purification:
    Purified by antigen-affinity chromatography.
  • Cat. No.:
    89358-612
  • Supplier no.:
    GTX116326

Specifications

About this item

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000, IP: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Type: Primary
Antigen: SIN3B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human