Specifications
- Antibody Type:Primary
- Antigen Name:Phosphodiesterase 4C
- Antigen Symbol:PDE4C
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:100 μg
- Gene ID:5143
- Antigen Synonyms:DPDE1
- Storage Buffer:Preservative: 0.02% Thimerosal / Merthiolate
- Storage Temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:0.5 mg/ml
- Immunogen:Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).
- Tested Applications:IP, WB
- Purification:Immunogen affinity purified
- Cat. No.:89367-344
- Supplier no.:GTX14608
Specifications
About this item
Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. cAMP-specific phosphodiesterase type-4 (PDE4) family is comprised of 4 genes (PDE4 A, B, C and D) with multiple splice variants generated by RNA splicing and use of alternate initiation sites. The cAMP-dependent protein kinase A modulates the enzyme activity of some PDE4 family members by phosphorylation/dephosphorylation mechanisms. Such short-term regulatory mechanisms are necessary for rapid changes in the cAMP levels in cells.
IP: Use at a dilution of 1/20. WB: Use at a dilution of 1/500. Predicted molecular weight: 80 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: PDE4C
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human