Specifications
- Antibody Type:Primary
- Antigen Name:Death associated protein 5
- Antigen Symbol:DAP5
- Clonality:Monoclonal
- Clone:39C534.1
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:50 μg
- Gene ID:1982
- Antigen Synonyms:Novel APOBEC-1 target 1|P97|Nat1|AAG1|Translation repressor NAT1|FLJ41344|Eukaryotic translation initiation factor 4 gamma 2|NAT1
- Amino Acid Number:796 to 812
- Storage Buffer:Preservative: 0.02% Sodium Azide; Constituents: PBS
- Sequence:APSKEQLEQEKQLLLSF
- Storage Temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:0.5 mg/ml
- Immunogen:This antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 796-812 (APSKEQLEQEKQLLLSF) of human DAP-5.
- Tested Applications:WB
- Purification:Immunogen affinity purified
- Cat. No.:89358-994
- Supplier no.:GTX11929
Specifications
About this item
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
WB: Use at a concentration of 1 - 2 ?g/ml. Detects a band of approximately 97 kDa. For optimal results, primary antibody incubations should be performed at room temperature. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: DAP5
Clonality: Monoclonal
Clone: 39C534.1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human