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39118 results for Proteins and Peptides

You searched for: Proteins and Peptides

Proteins and Peptides

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.

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Mouse Recombinant RESISTIN (from E. coli cells)

Mouse Recombinant RESISTIN (from E. coli cells)

Supplier: VWR International

Resistin, also known as FIZZ3, is a peptide hormone belonging to a class of cysteine-rich secreted proteins termed the resistin-like molecules (RELM) family. Mouse resistin, produced by adipocytes, is involved in insulin resistance and modulates glucose homeostasis and adipogenesis.

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Human Recombinant MIG/CXCL9 (from E. coli)

Human Recombinant MIG/CXCL9 (from E. coli)

Supplier: VWR International

Monokine induced by gamma interferon (MIG or CXCL9) is a T cell chemoattractant during neuroinflammatory events. MIG production is stimulated by interferon gamma (IFNɣ) and signals through the chemokine receptor CXCR3.

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Human Recombinant NAP-2 (from CHO cells)

Human Recombinant NAP-2 (from CHO cells)

Supplier: VWR International

Neutrophil activating peptide 2 (NAP-2), also known as CXCL7, is a member of the CXC family of chemokines. NAP-2 is a carboxyl-terminal fragment produced by proteolytic cleavage of the platelet basic protein (PBP). NAP-2 is released from platelets and binds to the receptors CXCR1 and CXCR2 to chemoattract and activate neutrophils during inflammatory events. 

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Mouse Recombinant IL-7 (from E. coli)

Mouse Recombinant IL-7 (from E. coli)

Supplier: VWR International

Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes.

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Human Recombinant MCP-4  (from E. coli)

Human Recombinant MCP-4 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as interleukin 1 (IL-1) and tumor necrosis factor alpha (TNF-α). MCP-4 is a ligand for the G protein coupled chemokine receptors CCR2, CCR3, and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils, and basophils during inflammation and allergic responses.

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Human Recombinant MCP-1 (from E. coli)

Human Recombinant MCP-1 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the CCR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflammation.

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Human Recombinant Visfatin (from E. coli)

Human Recombinant Visfatin (from E. coli)

Supplier: VWR International

Visfatin is an adipokine produced by visceral adipose tissue. Visfatin acts as a pro-inflammatory factor for peripheral blood mononuclear cells (PBMCs) and mimics the effects of insulin on adipocytes, monocytes, and hepatocytes.

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Mouse Recombinant MCP-1 (from E. coli)

Mouse Recombinant MCP-1 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the CCR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflammation.

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Human Recombinant MCP-3 (from E. coli)

Human Recombinant MCP-3 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.

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Human Recombinant FGF-8 (from E. coli)

Human Recombinant FGF-8 (from E. coli)

Supplier: VWR International

Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.

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Mouse Recombinant MIP-2 (from E. coli)

Mouse Recombinant MIP-2 (from E. coli)

Supplier: VWR International

Macrophage Inflammatory Protein 2 (MIP-2), also known as CXCL2, is a small cytokine that is secreted by monocytes and neutrophils at sites of inflammation. MIP-2 functions through the chemokine receptor CXCR2 to act as a chemotactic agent for leukocytes and hematopoietic cells.

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Mouse Recombinant MIP-1 B (from E. coli)

Mouse Recombinant MIP-1 B (from E. coli)

Supplier: VWR International

Macrophage inflammatory protein-1 beta (MIP-1 β), also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1 β signals through the chemokine receptor CCR5 to chemoattract immune cells.

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Human Recombinant GDF-5 (from E. coli)

Human Recombinant GDF-5 (from E. coli)

Supplier: VWR International

Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues.

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Dog Recombinant IL-2 (from E. coli)

Dog Recombinant IL-2 (from E. coli)

Supplier: VWR International

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Rat Recombinant EGF (from E. coli)

Rat Recombinant EGF (from E. coli)

Supplier: VWR International

Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR).

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Rat Recombinant TNF-A (from E. coli)

Rat Recombinant TNF-A (from E. coli)

Supplier: VWR International

Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2.

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Human Recombinant FLT-3 LIGAND (from E. coli)

Human Recombinant FLT-3 LIGAND (from E. coli)

Supplier: VWR International

FLT-3 Ligand is a growth factor that regulates proliferation of early hematopoietic cells. FLT-3 Ligand binds to cells expressing the tyrosine kinase receptor FLT-3.

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Human Recombinant GRO-B (from E. coli)

Human Recombinant GRO-B (from E. coli)

Supplier: VWR International

Growth regulated protein beta (GRO-β), also known as CXCL2, is a chemokine that is secreted by macrophages, neutrophils, and monocytes at sites of inflammation. GRO-β functions as a chemoattractant for leukocytes and hematopoietic stem cells. GRO-β activity is mediated through binding the G-protein-coupled chemokine receptor CXCR2.

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Rat Recombinant MCP-1 (from E. coli)

Rat Recombinant MCP-1 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the CCR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflammation.

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Mouse Recombinant MCP-2 (from E. coli)

Mouse Recombinant MCP-2 (from E. coli)

Supplier: VWR International

Monocyte chemotactic protein 2 (MCP-2), also known as CCL8, is a cytokine that is important during allergic and inflammatory responses. MCP-2 activates mast cells, eosinophils, and basophils through the G protein-coupled chemokine receptors CCR1, CCR2B, and CCR5.

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Mouse Recombinant TPO (from E. coli)

Mouse Recombinant TPO (from E. coli)

Supplier: VWR International

Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets.

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Human Recombinant GDNF (from E. coli cells)

Human Recombinant GDNF (from E. coli cells)

Supplier: VWR International

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

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Rat Recombinant SHH (from E. coli)

Rat Recombinant SHH (from E. coli)

Supplier: VWR International

Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.

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Mouse Recombinant Rank Ligand (from E. coli)

Mouse Recombinant Rank Ligand (from E. coli)

Supplier: VWR International

Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.

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Mouse Recombinant PDGF-AA (from E. coli)

Mouse Recombinant PDGF-AA (from E. coli)

Supplier: VWR International

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.

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Human Recombinant Hematopoietic Stem Cell Expansion Protein Bundle (from E. coli)

Human Recombinant Hematopoietic Stem Cell Expansion Protein Bundle (from E. coli)

Supplier: VWR International

Cytokines for expansion and cell culture of human hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential.

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Pig Recombinant IL-2 (from E. coli cells)

Pig Recombinant IL-2 (from E. coli cells)

Supplier: VWR International

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Dog Recombinant IL-2 (from E. coli)

Dog Recombinant IL-2 (from E. coli)

Supplier: VWR International

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.  

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Rat Recombinant FGF-9 (from E. coli)

Rat Recombinant FGF-9 (from E. coli)

Supplier: VWR International

Fibroblast growth factor 9 (FGF-9) is a mitogen and survival factor for nerve and mesenchymal cells. FGF-9 functions as an autocrine and paracrine factor to support the growth and survival of motor neurons and prostate tissue. FGF-9 expression in the gonad is also necessary for sex determination.

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Human Recombinant VEGF-121 (from E. coli)

Human Recombinant VEGF-121 (from E. coli)

Supplier: VWR International

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways.

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