You searched for: Tacrolimus monohydrate

Supplier: TCI America

CAS Number: 109581-93-3 MDL Number: MFCD11045918 Molecular Formula: C44H69NO12 Molecular Weight: 804.03 Purity/Analysis Method: 80.0% (HPLC) Form: Crystal Melting point (°C): 127 Storage Temperature: 0°C

Supplier: Ambeed

Tacrolimus monohydrate 98%

Supplier: Adipogen

Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B; calcineurin), leading to disruption of T cell activation. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Neuroprotective. Regulates nitric oxide neurotoxicity. Neurotransmitter. Ca2+ release compound. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis inducer.