Sulfamethazine sodium salt

Supplier: Thermo Scientific Chemicals

Sulfamethazine sodium salt

Supplier: TCI America

CAS Number: 1981-58-4 MDL Number: MFCD00068333 Molecular Formula: C12H14N4O2S Molecular Weight: 300.31 Purity/Analysis Method: 97.0% (HPLC,N) Form: Crystal Color: White Storage Temperature: 0-10°C

Supplier: MP Biomedicals

Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.