You searched for: Bupivacaine hydrochloride

Supplier: TCI America

CAS Number: 18010-40-7
MDL Number: MFCD00078956
Molecular Formula: C18H28N2O
Molecular Weight: 324.89
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 257

Supplier: MP Biomedicals

Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization.