Lenalidomide

Supplier: Thermo Scientific Chemicals

Lenalidomide ≥98%

Supplier: Abcam

Thalidomide analog and TNF-α inhibitor. Potent antitumor and anti-inflammatory effects. Modulates and potentiates host immune responses against multiple myeloma. Active in vitro.

Supplier: G-Biosciences

Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic.

Supplier: Ambeed

Lenalidomide 98%

Supplier: Matrix Scientific

(3S)-3-(4-AMINO-1-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)PIPERIDINE-2,6-DIONE MF=C13H13N3O3 MW=259.27 CAS=191732-72-6 MDL=MFCD22207056