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Anti-Bim/BOD Rabbit Polyclonal Antibody
Anti-Bim/BOD Rabbit Polyclonal Antibody
Catalog # 10049-812
Supplier:  Enzo Life Sciences
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Anti-Bim/BOD Rabbit Polyclonal Antibody
Catalog # 10049-812
Supplier:  Enzo Life Sciences
Supplier Number:  ADI-AAP-330-E
Restricted Products: To process your orders without delay, please provide the required business documentation to purchase this product.

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Specifications

  • Antibody Type:
    Primary
  • Antigen Symbol:
    Bim/BOD
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    100 µg
  • Environmentally Preferable:
  • Form:
    Liquid
  • Storage Buffer:
    PBS containing 0.02% sodium azide.
  • Storage Temperature:
    +4°C
  • Shipping Temperature:
    Blue Ice Not Frozen
  • Immunogen:
    Synthetic peptide corresponding to the sequence near the middle of human Bim/BOD.
  • Purification:
    purified by peptide affinity chromatography
  • Cat. No.:
    10049-812
  • Supplier no.:
    ADI-AAP-330-E

Specifications

About this item

Bim/BOD is a group of three splice variants, BimEL, BimL, and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bim is a critical regulator of lymphocyte homeostasis, acts as a barrier against autoimmune disease and is necessary for the apoptotic response to certain stress signals. All isoforms of Bim contain the C-terminal Bcl-2 homology domain known as BH3. Certain apoptotic stimuli release Bim from the complex which allows it to translocate to the mitochondria and bind to Bcl-2 or its homologues, thereby promoting apoptosis.

Type: Primary
Antigen: Bim/BOD
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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