Recombinant proteins
Optimizing recombinant protein manufacturing with advanced solutions.
Recombinant Protein Production
Recombinant proteins are manufactured using microbial (E. coli) expression systems. Multiple protein expression, aggregation, and filtration steps are required to yield protein-based therapeutic substances such as insulin, erythropoietin, and enzymes.
Maximize bioprocessing productivity with Avantor®
From upstream to downstream purification, through final fill, Avantor® partners with your team to help you achieve reliable results. We combine our extensive experience with a broad range of products that include cGMP fermentation materials to support cell growth, excipients, chromatography media to aid in recombinant protein purification, and single-use solutions to maximize the productivity of your bioprocessing systems.
Supporting GLP-1 therapeutics
Avantor® is well positioned to meet the critical challenges of companies developing and manufacturing next generation solutions to solve global health challenges – including GLP-1.
Recombinant protein manufacturing flow
Upstream processing
Whether your fermentation media are animal-based materials or “animal-free,” our fermentation products — such as Avantor J.T.Baker® IPTG used during microbial fermentation to induce the expression of recombinant proteins — support cell growth and productivity while meeting the required quality and performance parameters. We also provide centrifuges and reagents for primary recovery, concentration, and clarification process steps.
Our industry-leading Avantor J.T.Baker® brand buffer product line and J.T.Baker® brand BAKERBOND™ chromatography resins, including the BAKERBOND® PROchievA™ recombinant protein A resin, are trusted for high performance in recombinant proteins manufacturing. Backed by more than four decades of chromatography experience, we also provide downstream optimization services, including:
- Column packing
- Process development support
- Custom chromatography resins
- Column cleaning and storage recommendations
Avantor offers the required finished packaging vials and stoppers you need to progress from the drug substance to the final injectable drug product. We also carry an industry-leading excipient product line, including stabilizers and preservatives that meet stringent internal and external quality requirements.
Scale your recombinant protein production using our single-use components, assemblies, and systems. Our technical experts can collaborate with you to customize products to meet the specifications needed for your application.
Maintaining aseptic conditions during the manufacturing or down packing process is part of managing your risk. We offer products from industry-leading manufacturers and support from our teams of specialists who have the technical and industry experience to recommend the best solutions to meet your needs.
How Avantor® can help
At Avantor, we have a deep understanding of bioprocessing workflows and regulatory environments. Our global distribution network and wide range of services can help you develop more efficient recombinant protein manufacturing processes. We deliver high-quality products with our streamlined purchasing experience. Our commitment to quality and innovation is proven and emphasized at every scale, making us a trusted partner.
Innovative products and solutions for recombinant protein production
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