Custom fit your mAbs downstream process
You have developed a unique monoclonal antibody therapy and it requires a unique manufacturing process. You need a partner who knows the ins and outs of the downstream process and which holistic solutions will work best for you.
Capitalize on Avantor’s technical expertise and consultative approach to improve productivity, maximize resource use and mitigate risk so you can focus on breakthrough innovations. We offer flexible solutions — tailored to your exact needs — that optimize every step of your mAb downstream process. From aseptic, single-use fluid pathways to more efficient buffer management, and effective viral inactivation to quality resins – we help reduce costs and process time and increase downstream yield.
Customize and streamline your mAbs downstream operations
Comprehensive and customized support to reduce viral burden downstream
Our scientists and application specialists understand the complexities of mAbs viral clearance and provide options for removing critical impurities. This consultative approach is supported by innovative products, such as a sustainable alternative, easy-to-use viral inactivation solution, high performance chromatography resins and buffers, and customized, system-agnostic fluid handling technologies. We tailor our approach to meet your needs, and effectively remove the burden of viral and other impurities downstream.
Expert strategies to improve mAb capture productivity
Rely on our scientific and technical expertise to improve the productivity of the protein capture and further chromatography steps with the right choice of high-capacity resins and buffers that meet critical quality attributes and improve protein recovery. This in-depth application knowledge allows us to handle increased upstream titers with faster processing times, decreased costs and better yields for enhanced purification efficiency of your monoclonal antibody.
Integrated buffer preparation solutions that optimize your mAbs process
J.T. Baker® Viral Inactivation Solution
Improve viral inactivation efficiency and minimize introduction of impurities.
PROchievA™ recombinant protein A
Enhance your separation power and increase product purity.
Our value section
Custom fit your downstream process
We collaborate to design flexible solutions for every step in the process — from buffer management to viral inactivation, chromatography and viral clearance — that can be configured for your unique needs.