650 Results for: "Shenandoah Biotechnology"

Supplier: Shenandoah Biotechnology

Stromal cell-derived factor-1 beta (SDF-1β), also called CXCL12b, is one of two SDF-1 splice variants made by a wide variety of cell s upon stimulation by inflammatory cytokines. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligan d signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Receptor activator of nuclear factor kappa-B Ligand (RANKL) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANKL plays a critical role in bone metabolism and osteoclast differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Growth regulated protein gamma (GRO-gamma), also called CXCL3, acts through the chemokine receptor CXCR2 to promote monocyte migrati on and adhesion. GRO-gamma also induces the migration of cerebellar granule neuron precursor cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Thymic stromal lymphopoietin (TSLP) is a hematopoietic cytokine produced in several tissues including the heart, liver and prostate. TSLP induces the release of T-cell attracting chemokines from monocyte. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocyte s. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10Rbeta chains. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. 1 * 20 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte prolifera tion, terminal differentiation, and activation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Acidic fibroblast growth factor (aFGF), also known as FGF1, is a potent inducer of DNA synthesis, cell proliferation, and has chemot actic activities. aFGF regulates cardiogenesis through protein kinase C signaling. 1 * 50 µG

Supplier: Shenandoah Biotechnology

Acidic fibroblast growth factor (aFGF), also known as FGF1, is a potent inducer of DNA synthesis, cell proliferation, and has chemot actic activities. aFGF regulates cardiogenesis through protein kinase C signaling. 1 * 100 µG

Supplier: Shenandoah Biotechnology

Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17BR receptor t o stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a c ritical role in the maintenance, survival, and differentiation of hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. acute lymphocytic leukemia B cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to acti vate receptor tyrosine kinase RET signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the a nterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. 1 * 5 mg

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 9 (IL-9) is a cytokine produced by type 2 T helper (Th2) cells and regulates hematopoietic cells. IL-9 signals through the interleukin 9 receptor (IL9R) to activate STAT signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 32 alpha (IL-32a) is one of six known splice variants of the IL-32 gene.  IL-32a induces the macrophage production of in flammatory cytokines, such as interleukin 8, tumor necrosis factor-alpha (TNF-a), and macrophage inflammatory protein 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 12 (IL-12) is an inducer of cell-mediated immunity and is produced by dendritic cells, macrophages, and B cells after an tigen stimulation. IL-12 functions to promote naïve T cell differentiation into the type 1 T helper cell (Th1) linea 1 * 2 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 10 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 10 µG

Supplier: Shenandoah Biotechnology

Fibroblast growth factor 7 (FGF7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cel l migration and differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through th e G protein-coupled receptors CCR1, CCR2, and CCR3. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 bi nds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 bi nds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Resistin-like molecule-beta (RELM-β) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. 1 * 100 µG

Supplier: Shenandoah Biotechnology

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 bi nds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 3 is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cell 1 * 2 µG