42864 Results for: "ProSci Inc."

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The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).

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This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.

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For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

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May be required for endoplasmic reticulum organization (By similarity).

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For WB starting dilution is: 1:1000.

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Putative solute transporter (Potential).

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For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

May be involved in transcriptional regulation.

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Anti-REGN88 Recombinant Antibody

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Anti-NOE-102 Recombinant Antibody

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Anti-MT203 Recombinant Antibody

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Anti-Anti-Beta7 Recombinant Antibody

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Anti-MLTA3698A Recombinant Antibody

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Anti-GBR500 Recombinant Antibody

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This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

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Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.

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The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

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This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

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For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein.

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For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.