148894 Results for: "Natural+Resources+Learning+Activities"

Supplier: DIDALAB

Extremely luminous beam, ideal for classroom experiments. Class IIIa (5 mW Power)

Supplier: G-Biosciences

The Affinity Chromatography kit teaches the basic principle of affinity chromatography utilising highly specific affinity columns. This lab activity involves preparation of a crude protein extract and running affinity exchange chromatography for isolation of a protein.

Supplier: Apollo Scientific

A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphate & stimulates ceramide-activated protein kinase.

Supplier: PHYWE

With a special addition, the analogue instrument can be turned into a digital instrument with simultaneous analogue display. In order to extend the measurement possibilities, there are also measurements for power and voltage amplification. The replaceable measuring areas are slid into a slot on the top of the instrument ('toaster principle').

Supplier: Bioss

Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.

Supplier: EDVOTEK

This Ready-to-Load™ kit shows how a restriction enzyme can be used to screen DNA for Sickle Cell Anaemia.

Supplier: Bioss

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Supplier: Bioss

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Supplier: 3B Scientific

Track with two trolleys and other accessories for investigating linear motion. The trolleys move with minimum friction on wheels with high-quality ball-bearings. They are fitted with magnets at their front ends for experiments involving both elastic and inelastic collisions.

Supplier: Bioss

GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

Supplier: 3B Scientific

Highly evacuated electron tube for determining the wavelength of electrons as a function of the anode voltage from the radii of the diffraction rings and the distance between the lattice planes of graphite (Debye-Scherrer-diffraction) and rendered visible on a fluorescent screen. Also intended for determining the wavelengths of monochromatic radiation at different anode voltages from the radii of the diffraction rings and the lattice plane spacing of graphite, as well as confirming de Broglie’s hypothesis.

Supplier: Bioss

GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

Supplier: Bioss

Triggers NCR3-dependent natural killer cell activation.

Supplier: Bioss

Triggers NCR3-dependent natural killer cell activation.

Supplier: Bioss

Triggers NCR3-dependent natural killer cell activation.

Supplier: EDVOTEK

Link important STEM concepts using Agarose Gel Electrophoresis.

Supplier: EDVOTEK

Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.

Supplier: DIDALAB

Educational Materials, Optics, Application: Physics, Translucent screen 20×20 cm, attached to a rod with Ø 10 mm

Supplier: Bioss

Triggers NCR3-dependent natural killer cell activation.

Supplier: EDVOTEK

Plasmid and lambda DNA are pre-digested with restriction endonucleases that recognise and cut double-stranded DNA within or near defined base sequences. Digests are separated by agarose gel electrophoresis.

Supplier: ENZO LIFE SCIENCES

Produced in a baculovirus expression system. Active recombinant human FAP (aa 29-760), representing a naturally-occurring cleaved (soluble) form.

Supplier: EDVOTEK

An infectious outbreak requires prompt and accurate identification of the biological agent. Often, early clinical symptoms are first identified in exposed individuals and then infectious agents are identified by lab tests. In this experiment, students transmit a simulated infectious agent (chemical dye) between classmates which is only visible under long UV light. The pattern of transmission and primary source is documented.

Supplier: Bioss

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Supplier: EDVOTEK

This experiment presents a bioterrorism scenario, with students examining a simulated DNA fingerprinting test for the detection of smallpox.

Supplier: 3B Scientific

Equipment set inclusive of digital multimeter for measuring electrochemical potentials of various metals in experiments.

Supplier: EDVOTEK

This experiment introduces students to the use of DNA fingerprinting in a simulated paternity determination. A child's DNA fingerprint is compared with his parents.

Supplier: Bioss

The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.

Supplier: DIDALAB

Prism made of standard optical glass with index near to 1,52. Equilateral dispersing prisms are used for wavelength separation applications. Intended for demonstration experiments of light dispersion.

Supplier: Bioss

Triggers NCR3-dependent natural killer cell activation.

Supplier: DIDALAB

This comprehensive optical pack allows you to implement and study the basic principles of polarisation of light.