1282 Results for: "MEDCHEMEXPRESS"

Sort By

FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically target 1 * 1 Each

Supplier: MEDCHEMEXPRESS

FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically target 1 * 1 Each

Expand 1 Items

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 1 * 25 mg

Supplier: MEDCHEMEXPRESS

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 1 * 25 mg

Expand 1 Items

Zanubrutinib (BGB-3111) is a selective and orally active Bruton tyrosine kinase (Btk) inhibitor (IC50: 0.3 nM)[1][2]. 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Zanubrutinib (BGB-3111) is a selective and orally active Bruton tyrosine kinase (Btk) inhibitor (IC50: 0.3 nM)[1][2]. 1 * 5 mg

Expand 1 Items

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and ins ulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on 1 * 250 mg

Supplier: MEDCHEMEXPRESS

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and ins ulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on 1 * 250 mg

Expand 1 Items

Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cance r. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunction 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cance r. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunction 1 * 5 mg

Expand 1 Items

Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer’s disease (AD)[1]. Azeliragon also 1 * 100 mg

Supplier: MEDCHEMEXPRESS

Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer’s disease (AD)[1]. Azeliragon also 1 * 100 mg

Expand 1 Items

Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor[1]. Z-IETD-FMK is also a granzyme B inhibito r[5]. 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor[1]. Z-IETD-FMK is also a granzyme B inhibito r[5]. 1 * 5 mg

Expand 1 Items

Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3K δ, PI3Kα, PI3Kγ and PI3Kβ, respectively. 1 * 200 mg

Supplier: MEDCHEMEXPRESS

Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3K δ, PI3Kα, PI3Kγ and PI3Kβ, respectively. 1 * 200 mg

Expand 1 Items

Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives[1]. 1 * 100 mg

Supplier: MEDCHEMEXPRESS

Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives[1]. 1 * 100 mg

Expand 1 Items

UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proli feration and has cardioprotective and neural regeneration effects[1]. 1 * 25 mg

Supplier: MEDCHEMEXPRESS

UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proli feration and has cardioprotective and neural regeneration effects[1]. 1 * 25 mg

Expand 1 Items

Catecholamine neurotransmitter, D2 dopamine receptor agonist Dopamine (TH) 10mg 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Catecholamine neurotransmitter, D2 dopamine receptor agonist Dopamine (TH) 10mg 1 * 10 mg

Expand 1 Items

AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of [1]. 1 * 5 mg

Supplier: MEDCHEMEXPRESS

AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of [1]. 1 * 5 mg

Expand 1 Items

Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozan tinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively) 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozan tinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively) 1 * 10 mg

Expand 1 Items

Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) ta rgets to the SARS-CoV-2 virus and can be used for COVID-19 research[1]. 1 * 50 mg

Supplier: MEDCHEMEXPRESS

Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) ta rgets to the SARS-CoV-2 virus and can be used for COVID-19 research[1]. 1 * 50 mg

Expand 1 Items

Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib has anti-tumor ac tivity[1][2]. Elimusertib can be used for the research of solid tumors and lymphomas[3]. 1 * 50 mg

Supplier: MEDCHEMEXPRESS

Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib has anti-tumor ac tivity[1][2]. Elimusertib can be used for the research of solid tumors and lymphomas[3]. 1 * 50 mg

Expand 1 Items

Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents bi nding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humani 1 * 1 mg

Supplier: MEDCHEMEXPRESS

Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents bi nding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humani 1 * 1 mg

Expand 1 Items

Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory disea 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory disea 1 * 5 mg

Expand 1 Items

Roxadustat is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoie sis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin[1]. 1 * 100 mg

Supplier: MEDCHEMEXPRESS

Roxadustat is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoie sis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin[1]. 1 * 100 mg

Expand 1 Items

Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0 .072 μM. Denifanstat has the potential for fatty liver disease and cancer research[1][2]. 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0 .072 μM. Denifanstat has the potential for fatty liver disease and cancer research[1][2]. 1 * 5 mg

Expand 1 Items

G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM for human G6P D. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production i 1 * 5 mg

Supplier: MEDCHEMEXPRESS

G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM for human G6P D. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production i 1 * 5 mg

Expand 1 Items

Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Fav ipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymera 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Fav ipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymera 1 * 5 mg

Expand 1 Items

Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs o f 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathologi 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs o f 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathologi 1 * 10 mg

Expand 1 Items

AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with Kis of 2.3 nM and 10 nM, respectively. 1 * 100 mg

Supplier: MEDCHEMEXPRESS

AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with Kis of 2.3 nM and 10 nM, respectively. 1 * 100 mg

Expand 1 Items

Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and CO 1 * 200 mg

Supplier: MEDCHEMEXPRESS

Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and CO 1 * 200 mg

Expand 1 Items

Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that target s the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of t 1 * 1 mg

Supplier: MEDCHEMEXPRESS

Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that target s the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of t 1 * 1 mg

Expand 1 Items

A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. A-1155463 is a click chemistry rea gent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules 1 * 5 mg

Supplier: MEDCHEMEXPRESS

A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. A-1155463 is a click chemistry rea gent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules 1 * 5 mg

Expand 1 Items

DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradati on of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-depend 1 * 25 mg

Supplier: MEDCHEMEXPRESS

DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradati on of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-depend 1 * 25 mg

Expand 1 Items

MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylaurista tin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and 1 * 50 mg

Supplier: MEDCHEMEXPRESS

MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylaurista tin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and 1 * 50 mg

Expand 1 Items

Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and i 1 * 5 g

Supplier: MEDCHEMEXPRESS

Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and i 1 * 5 g