1277 Results for: "MEDCHEMEXPRESS"
CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. 1 * 1 mg
Supplier: MEDCHEMEXPRESS
CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. 1 * 1 mg
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Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM. 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM. 1 * 10 mg
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TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a fa ster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively re 1 * 1 g
Supplier: MEDCHEMEXPRESS
TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a fa ster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively re 1 * 1 g
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C75 is a synthetic fatty-acid synthase (FASN) inhibitor inhibits prostate cancer cells PC3 with an IC50 of 35 μM[1][2][3]. C75 is a potent CPT1A activator[5]. 1 * 25 mg
Supplier: MEDCHEMEXPRESS
C75 is a synthetic fatty-acid synthase (FASN) inhibitor inhibits prostate cancer cells PC3 with an IC50 of 35 μM[1][2][3]. C75 is a potent CPT1A activator[5]. 1 * 25 mg
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Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids[1]. 1 * 100 mg
Supplier: MEDCHEMEXPRESS
Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids[1]. 1 * 100 mg
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Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an appa rent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGF 1 * 1 g
Supplier: MEDCHEMEXPRESS
Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an appa rent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGF 1 * 1 g
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YM-201636 is a potent and selective PIKfyve inhibitor with an IC50 of 33 nM. YM-201636 also inhibits p110α with an IC50 of 3.3 μM. Y M-201636 inhibits retroviral replication. 1 * 25 mg
Supplier: MEDCHEMEXPRESS
YM-201636 is a potent and selective PIKfyve inhibitor with an IC50 of 33 nM. YM-201636 also inhibits p110α with an IC50 of 3.3 μM. Y M-201636 inhibits retroviral replication. 1 * 25 mg
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Bersiporocin is a prolyl-tRNA synthetase inhibitor. Bersiporocin has an IC50 of ≤100 nM for phosphoribosylpyrophosphate synthetase ( PRS). Bersiporocin can be used for the research of antifibrotic. 1 * 1 mg
Supplier: MEDCHEMEXPRESS
Bersiporocin is a prolyl-tRNA synthetase inhibitor. Bersiporocin has an IC50 of ≤100 nM for phosphoribosylpyrophosphate synthetase ( PRS). Bersiporocin can be used for the research of antifibrotic. 1 * 1 mg
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Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be us ed in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2)[1]. 1 * 25 mg
Supplier: MEDCHEMEXPRESS
Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be us ed in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2)[1]. 1 * 25 mg
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ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenche d by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. 1 * 10 mg
Supplier: MEDCHEMEXPRESS
ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenche d by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. 1 * 10 mg
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FT3967385 is a novel USP30 inhibitor that recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation. 1 * 100 mg
Supplier: MEDCHEMEXPRESS
FT3967385 is a novel USP30 inhibitor that recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation. 1 * 100 mg
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CADD522 is a RUNX2-DNA binding inhibitor (downregulates RUNX2-mediated transcription of downstream target genes), with an IC50 of 10 nM. CADD522 inhibits primary tumor growth and experimental metastasis of tumor cells in the lungs of immune-compromi 1 * 100 mg
Supplier: MEDCHEMEXPRESS
CADD522 is a RUNX2-DNA binding inhibitor (downregulates RUNX2-mediated transcription of downstream target genes), with an IC50 of 10 nM. CADD522 inhibits primary tumor growth and experimental metastasis of tumor cells in the lungs of immune-compromi 1 * 100 mg
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Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agen t, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide syn 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agen t, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide syn 1 * 5 mg
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Carotegrast methyl (AJM300) is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast m ethyl, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl prevents the development of colitis i 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Carotegrast methyl (AJM300) is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast m ethyl, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl prevents the development of colitis i 1 * 10 mg
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Sepantronium bromide (YM-155) is a survivin inhibitor with an IC50 of 0.54 nM[1]. 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Sepantronium bromide (YM-155) is a survivin inhibitor with an IC50 of 0.54 nM[1]. 1 * 5 mg
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Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the G ABA degradating enzyme GABA-T. 1 * 1 g
Supplier: MEDCHEMEXPRESS
Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the G ABA degradating enzyme GABA-T. 1 * 1 g
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Rosnilimab is a humanized IgG1-κ antibody targeting to PD-1[1][2]. 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Rosnilimab is a humanized IgG1-κ antibody targeting to PD-1[1][2]. 1 * 10 mg
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Darolutamide (ODM-201 BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay. 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Darolutamide (ODM-201 BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay. 1 * 5 mg
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KGF-2/FGF-10 Protein, Human (169a.a) is a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the gro wth, proliferation, and differentiation of epithelial cells and can enhance corneal wound healing. 1 * 500 µG
Supplier: MEDCHEMEXPRESS
KGF-2/FGF-10 Protein, Human (169a.a) is a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the gro wth, proliferation, and differentiation of epithelial cells and can enhance corneal wound healing. 1 * 500 µG
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4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments . 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed a 1 * 100 mg
Supplier: MEDCHEMEXPRESS
4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments . 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed a 1 * 100 mg
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Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induc 1 * 50 mg
Supplier: MEDCHEMEXPRESS
Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induc 1 * 50 mg
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Monomethyl auristatin E (MMAE SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by i nhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to 1 * 100 mg
Supplier: MEDCHEMEXPRESS
Monomethyl auristatin E (MMAE SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by i nhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to 1 * 100 mg
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Adavosertib (AZD-1775 MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM. 1 * 200 mg
Supplier: MEDCHEMEXPRESS
Adavosertib (AZD-1775 MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM. 1 * 200 mg
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Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. 1 * 200 mg
Supplier: MEDCHEMEXPRESS
Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. 1 * 200 mg
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Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell u 1 * 500 mg
Supplier: MEDCHEMEXPRESS
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell u 1 * 500 mg
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Trametinib (GSK1120212 JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametini b activates autophagy and induces apoptosis[1][2]. 1 * 50 mg
Supplier: MEDCHEMEXPRESS
Trametinib (GSK1120212 JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametini b activates autophagy and induces apoptosis[1][2]. 1 * 50 mg
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Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM[1]. 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM[1]. 1 * 5 mg
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8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Br omo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells[1][2]. 1 * 100 mg
Supplier: MEDCHEMEXPRESS
8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Br omo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells[1][2]. 1 * 100 mg
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MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki va lues of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of mu 1 * 5 mg
Supplier: MEDCHEMEXPRESS
MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki va lues of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of mu 1 * 5 mg
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TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively. 1 * 50 mg
Supplier: MEDCHEMEXPRESS
TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively. 1 * 50 mg
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: BOCHEM
: VWR Collection
: DWK Life Sciences
: Thermo Fisher Scientific
: VWR Collection
: Oxford Nanopore Technologies
: Industrial Physics
: AAT BIOQUEST
: Integra
: Palbam
: VWR Collection
: Integra
: VWR Collection
: FACELLITATE
: NANOENTEK
: Greiner Bio-One