1259 Results for: "MEDCHEMEXPRESS"
(Rac)-JBJ-04-125-02 1 * 50 mg
Supplier: MEDCHEMEXPRESS
(Rac)-JBJ-04-125-02 1 * 50 mg
Expand 1 Items
TAK-243 (Synonyms: MLN7243) - 10mg 1 * 10 mg
Supplier: MEDCHEMEXPRESS
TAK-243 (Synonyms: MLN7243) - 10mg 1 * 10 mg
Expand 1 Items
Zanubrutinib 50mg 1 * 50 mg
Supplier: MEDCHEMEXPRESS
Zanubrutinib 50mg 1 * 50 mg
Expand 1 Items
Upadacitinib (10 mM * 1 mL in DMSO) 1 * 1 mL
Supplier: MEDCHEMEXPRESS
Upadacitinib (10 mM * 1 mL in DMSO) 1 * 1 mL
Expand 1 Items
Neurokin 1 receptor agonist Substance P 5mg 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Neurokin 1 receptor agonist Substance P 5mg 1 * 5 mg
Expand 1 Items
FGF basic/bFGF Protein, Human (146a.a) 1 * 50 µG
Supplier: MEDCHEMEXPRESS
FGF basic/bFGF Protein, Human (146a.a) 1 * 50 µG
Expand 1 Items
KSQ-4279(Purity 98%) 500mg 1 * 500 mg
Supplier: MEDCHEMEXPRESS
KSQ-4279(Purity 98%) 500mg 1 * 500 mg
Expand 1 Items
RMC-5552 mTORC1 inhibitor / 5mg 1 * 5 mg
Supplier: MEDCHEMEXPRESS
RMC-5552 mTORC1 inhibitor / 5mg 1 * 5 mg
Expand 1 Items
TC-S 7005 - 5 MG 1 * 5 mg
Supplier: MEDCHEMEXPRESS
TC-S 7005 - 5 MG 1 * 5 mg
Expand 1 Items
Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR 3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR 3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be 1 * 10 mg
Expand 1 Items
GW4869 is a noncompetitive neutral sphingomyelinase (N-SMase) inhibitor with an IC50 of 1 μM. GW4869 is an inhibitor of exosome biog enesis/release[1][2][3][4]. 1 * 25 mg
Supplier: MEDCHEMEXPRESS
GW4869 is a noncompetitive neutral sphingomyelinase (N-SMase) inhibitor with an IC50 of 1 μM. GW4869 is an inhibitor of exosome biog enesis/release[1][2][3][4]. 1 * 25 mg
Expand 1 Items
Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2]. 1 * 200 mg
Supplier: MEDCHEMEXPRESS
Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2]. 1 * 200 mg
Expand 1 Items
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGF 1 * 100 mg
Supplier: MEDCHEMEXPRESS
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGF 1 * 100 mg
Expand 1 Items
GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably 1 * 10 mg
Supplier: MEDCHEMEXPRESS
GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably 1 * 10 mg
Expand 1 Items
Omaveloxolone (RTA 408) is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO). Omave loxolone attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling. 1 * 25 mg
Supplier: MEDCHEMEXPRESS
Omaveloxolone (RTA 408) is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO). Omave loxolone attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling. 1 * 25 mg
Expand 1 Items
AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinf lammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[1][2]. 1 * 50 mg
Supplier: MEDCHEMEXPRESS
AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinf lammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[1][2]. 1 * 50 mg
Expand 1 Items
GSK343 is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM. 1 * 100 mg
Supplier: MEDCHEMEXPRESS
GSK343 is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM. 1 * 100 mg
Expand 1 Items
Baricitinib (LY3009104 INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Baricitinib (LY3009104 INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. 1 * 10 mg
Expand 1 Items
JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectivel y[1]. 1 * 100 mg
Supplier: MEDCHEMEXPRESS
JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectivel y[1]. 1 * 100 mg
Expand 1 Items
Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM ROCK-II Ki=300 nM). Y -27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. 1 * 10 mg
Supplier: MEDCHEMEXPRESS
Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM ROCK-II Ki=300 nM). Y -27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. 1 * 10 mg
Expand 1 Items
Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research[1][2][3]. 1 * 200 mg
Supplier: MEDCHEMEXPRESS
Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research[1][2][3]. 1 * 200 mg
Expand 1 Items
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an aut ophagy activator. 1 * 5 mg
Supplier: MEDCHEMEXPRESS
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an aut ophagy activator. 1 * 5 mg
Expand 1 Items
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1]. 1 * 1 mg
Supplier: MEDCHEMEXPRESS
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1]. 1 * 1 mg