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1259 results for "MEDCHEMEXPRESS"

1259 Results for: "MEDCHEMEXPRESS"

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FEDRATINIB 1 * 1 g

Supplier: MEDCHEMEXPRESS

FEDRATINIB 1 * 1 g

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(Rac)-JBJ-04-125-02 1 * 50 mg

Supplier: MEDCHEMEXPRESS

(Rac)-JBJ-04-125-02 1 * 50 mg

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TAK-243 (Synonyms: MLN7243) - 10mg 1 * 10 mg

Supplier: MEDCHEMEXPRESS

TAK-243 (Synonyms: MLN7243) - 10mg 1 * 10 mg

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Zanubrutinib 50mg 1 * 50 mg

Supplier: MEDCHEMEXPRESS

Zanubrutinib 50mg 1 * 50 mg

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ML385 1 * 50 mg

Supplier: MEDCHEMEXPRESS

ML385 1 * 50 mg

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IRAK4-IN-1 1 * 5 mg

Supplier: MEDCHEMEXPRESS

IRAK4-IN-1 1 * 5 mg

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Upadacitinib (10 mM * 1 mL in DMSO) 1 * 1 mL

Supplier: MEDCHEMEXPRESS

Upadacitinib (10 mM * 1 mL in DMSO) 1 * 1 mL

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Neurokin 1 receptor agonist Substance P 5mg 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Neurokin 1 receptor agonist Substance P 5mg 1 * 5 mg

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NVS-PAK1-1 1 * 10 mg

Supplier: MEDCHEMEXPRESS

NVS-PAK1-1 1 * 10 mg

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FGF basic/bFGF Protein, Human (146a.a) 1 * 50 µG

Supplier: MEDCHEMEXPRESS

FGF basic/bFGF Protein, Human (146a.a) 1 * 50 µG

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KSQ-4279(Purity 98%) 500mg 1 * 500 mg

Supplier: MEDCHEMEXPRESS

KSQ-4279(Purity 98%) 500mg 1 * 500 mg

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RMC-5552 mTORC1 inhibitor / 5mg 1 * 5 mg

Supplier: MEDCHEMEXPRESS

RMC-5552 mTORC1 inhibitor / 5mg 1 * 5 mg

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BRUSATOL 1 * 25 mg

Supplier: MEDCHEMEXPRESS

BRUSATOL 1 * 25 mg

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TC-S 7005 - 5 MG 1 * 5 mg

Supplier: MEDCHEMEXPRESS

TC-S 7005 - 5 MG 1 * 5 mg

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eIF4A3-IN -1 1 * 10 mg

Supplier: MEDCHEMEXPRESS

eIF4A3-IN -1 1 * 10 mg

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Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR 3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR 3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be 1 * 10 mg

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GW4869 is a noncompetitive neutral sphingomyelinase (N-SMase) inhibitor with an IC50 of 1 μM. GW4869 is an inhibitor of exosome biog enesis/release[1][2][3][4]. 1 * 25 mg

Supplier: MEDCHEMEXPRESS

GW4869 is a noncompetitive neutral sphingomyelinase (N-SMase) inhibitor with an IC50 of 1 μM. GW4869 is an inhibitor of exosome biog enesis/release[1][2][3][4]. 1 * 25 mg

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Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2]. 1 * 200 mg

Supplier: MEDCHEMEXPRESS

Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2]. 1 * 200 mg

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Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGF 1 * 100 mg

Supplier: MEDCHEMEXPRESS

Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGF 1 * 100 mg

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GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably 1 * 10 mg

Supplier: MEDCHEMEXPRESS

GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably 1 * 10 mg

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Omaveloxolone (RTA 408) is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO). Omave loxolone attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling. 1 * 25 mg

Supplier: MEDCHEMEXPRESS

Omaveloxolone (RTA 408) is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO). Omave loxolone attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling. 1 * 25 mg

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AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinf lammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[1][2]. 1 * 50 mg

Supplier: MEDCHEMEXPRESS

AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinf lammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[1][2]. 1 * 50 mg

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GSK343 is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM. 1 * 100 mg

Supplier: MEDCHEMEXPRESS

GSK343 is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM. 1 * 100 mg

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Baricitinib (LY3009104 INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Baricitinib (LY3009104 INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. 1 * 10 mg

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JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectivel y[1]. 1 * 100 mg

Supplier: MEDCHEMEXPRESS

JNK-IN-8 (JNK Inhibitor XVI) is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectivel y[1]. 1 * 100 mg

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Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM ROCK-II Ki=300 nM). Y -27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. 1 * 10 mg

Supplier: MEDCHEMEXPRESS

Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM ROCK-II Ki=300 nM). Y -27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. 1 * 10 mg

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Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research[1][2][3]. 1 * 200 mg

Supplier: MEDCHEMEXPRESS

Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research[1][2][3]. 1 * 200 mg

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Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an aut ophagy activator. 1 * 5 mg

Supplier: MEDCHEMEXPRESS

Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an aut ophagy activator. 1 * 5 mg

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S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1]. 1 * 1 mg

Supplier: MEDCHEMEXPRESS

S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1]. 1 * 1 mg

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