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Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.

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The objective of this experiment is to investigate the genetic basis of beak size variation in Galapagos finches before and after a drought event using Restriction Fragment Length Polymorphism (RFLP) analysis.

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In this experiment, students study the diversity of fish using pre-stained, lyophilised proteins. Total protein from perch, walleye and salmon is extracted and pre-stained using an indicator dye. Each fish protein sample has a characteristic banding pattern when separated by denaturing SDS-polyacrylamide gel electrophoresis, which can be used to identify the specific species.

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Sturdily designed handheld pipettes with volumes ranging from 0,1 to 5000 µl. They are easy to use, accurate and use standard micropipette tips.

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This experiment introduces chromatographic theory and methods of thin layer chromatography (TLC). A mixture of dyes are separated on a cellulose-based TLC plate using different solvent systems.

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Pipette, Pasteur / transfer

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Students learn about DNA polymorphisms by amplifying DNA regions that vary between wild and mutant Drosophila. Amplified DNA from wild-type and white-eyed flies are separated by agarose gel electrophoresis and analysed.

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Experimentation kits, human PCR Tool Box™

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This LabStation provides all that is needed to run any Edvotek DNA or dye electrophoresis kits with students.

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Controller, pipette, Blue

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Ready-to-Load™ kit to show how electrophoresis separates molecules on the basis of size and charge.

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Digital stainless steel shaking water bath, designed for when incubation of samples together with precise aeration and agitation is required.

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Coronary heart disease and stroke are major causes of death in the Western world. Elevated blood cholesterol levels are a serious risk factor in both conditions. The genetic disease familial hypersholesterolemia (FH) causes an increase in blood levels of the bad form of cholesterol, low density lipoprotein (LDL). In untreated patients with the mutant FH gene, the condition can cause premature death. This experiment introduces the colorimetric enzymatic reaction which is the basis of the clinical cholesterol test. In addition, using agarose gel electrophoresis, students can analyse a simulated genetic screening for a disease.

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Students learn the basic principles of the Enzyme-linked Immunosorbent Assay (ELISA) using this precise and sensitive antibody-based detection kit.

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This simulation experiment demonstrates the process of DNA amplification by PCR and how the amplified product is detected by separating the reaction mixture by agarose gel electrophoresis.

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This kit is for teaching students how people's physical traits are a reflection of their genes. In this simulation, students use electrophoresis to separate dyes which represent genetic traits.

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Six groups of students can load their own individual gels and the six gels can be run together in 30 to 40 minutes. No need for gel taping and gels can be poured quickly and easily using the gel tray sealing rubber end caps.

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Link important STEM concepts using Agarose Gel Electrophoresis.

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Most molecules have a net charge within a pH range of 2 to 10. When the pH is altered, the net charge on molecules can change drastically. In this experiment, a mixture of two chemicals is absorbed onto a solid support ion-exchange column and separated during elution under conditions that influence their net charge.

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EVT 300 power supplies can operate M6Plus units, two M12 units or two HexaGels (at 75 V). The EVT 300 runs gels as fast as 20 to30 minutes (at 150 V).

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In this PCR experiment, students make billions of copies of a small amount of DNA in only 90 minutes. They just need to mix template DNA and primers with PCR beads that contain all of the other components required to carry out a PCR reaction. Students see the increasing amounts of DNA for themselves, taking samples every few cycles and analysing them on a DNA gel.

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In DNA fingerprinting, variable number tandem repeats (VNTR) are used to identify individuals. Using this kit, students type themselves at the D1S80 locus on chromosome 1. This region contains between 14 and 40 copies of a 16 base pair repeat.

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Students can build a model of DNA using this simple and colourful system.

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In this kit, a set of multi-coloured links demonstate a variety of molecular biology simulations. Students learn about digesting DNA with restriction enzymes, cloning genes in plasmids, protein structure, and more.

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Experiment using fluorescence and electrophoresis to solve the mystery of the invisible bands.

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20 µg for 20 gels.

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The second assay used to confirm a positive HIV ELISA result is the Western blot. Using this kit, students separate protein samples from hypothetical patients on agarose gels. The proteins are then transferred to a membrane and simulated HIV proteins are detected.

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Stainless steel lid, For: 5027

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This Ready-to-Load™ kit shows how a restriction enzyme can be used to screen DNA for Sickle Cell Anaemia.

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Genetic testing can be used to identify people with a genetic condition which caused them to have an elevated level of cholesterol and which can be fatal. Students can see how genetic testing is carried out and learn about DNA electrophoresis.