Supplier: Cayman Chemical

BSA-Palmitate saturated fatty acid complex is composed of palmitic acid and bovine serum albumin (BSA) at an approximately 6:1 molar ratio of palmitate:BSA. It can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies.

Supplier: Cayman Chemical

Hygromycin B

Supplier: Cayman Chemical

Interferon regulatory factor 3 (IRF3) is a member of the IRF family that plays a crucial role in activation of innate immunity and inflammation in response to viral infection, functioning as a molecular switch for antiviral activity. Double-stranded RNA generated during a viral infection leads to IRF3 activation through serine/threonine phosphorylation by TBK1 (Item No. 22817) or IKKε (IKBKE) kinases, which induces a conformational change leading to its dimerization, nuclear localization, and association with CREB binding protein (CREBBP)/p300. The complex formed by this association, known as DRAF1, activates transcription of interferon α (IFN-α) and IFN-β as well as other IFN-induced genes, which play a critical role in the type 1 IFN-dependent immune response. Cayman’s IRF3 Polyclonal Antibody can be used for Western blot and ELISA applications. The antibody recognizes IRF3 at ~47 kDa from human samples.

Supplier: Cayman Chemical

Echinocandin B inhibits 1,3-β glucan synthase; inhibits incorporation of radiolabeled glucose into alkali-insoluble glucan by S. cerevisiae spheroplasts; inhibits growth of C. albicans in vitro (MIC = 3.9 µg/ml after 2 days)

Supplier: Cayman Chemical

Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

Supplier: Cayman Chemical

iFSP1 is an inhibitor of apoptosis inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1)

Supplier: Cayman Chemical

BSA-Oleate monounsaturated fatty acid complex is composed of oleic acid and bovine serum albumin (BSA) at an approximately 6:1 molar ratio of oleate:BSA. It has been used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies.

Supplier: Cayman Chemical

Tyrosol is a phenol that has been found in olives and olive oil and has diverse biological activities.

Supplier: Cayman Chemical

5-Fluoro-2'-deoxyuridine (floxuridine)

Supplier: Cayman Chemical

Anti-GPR12 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC.

Supplier: Cayman Chemical

Baicalein

Supplier: Cayman Chemical

Potassium phosphate buffer solution (0,5 mol/l), pH value: 8,0

Supplier: Cayman Chemical

3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate

Supplier: Cayman Chemical

DepNA (decanoyl-p-nitroaniline)

Supplier: Cayman Chemical

Anti-Nitrotyrosine Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

10-Acetyl-3,7-dihydroxyphenoxazine (ADHP) is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H₂O₂.

Supplier: Cayman Chemical

Natamycin is a naturally-occurring macrolide polyene antifungal agent produced during fermentation by the bacterium S. natalensis, commonly found in soil. Used to treat fungal infections, including candida, aspergillus, cephalosporium, fusarium, and penicillium.

Supplier: Cayman Chemical

18β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC₅₀ = 35 μM). At 100 mg/kg/day, 18β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. It inhibits mammalian DNA polymerases α, γ, κ and λ with IC₅₀ values of 16,1, 19,3, 15,8 and 13,7 μM, respectively. At 100-200 μM, 18β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

Supplier: Cayman Chemical

Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation and apoptosis are features of leukotoxin toxicity. In renal phydrolysesroximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

Supplier: Cayman Chemical

Phytanic acid is a saturated 20-carbon branched-chain fatty acid which can only be derived from dietary sources. In cases of peroxisomal disorders, elevated levels of phytanic acid are observed, and this is linked to diseases such as infantile phytanic acid storage disease and Refsum’s disease.

Supplier: Cayman Chemical

Thioisonicotinamide

Supplier: Cayman Chemical

γ-Linolenic acid methyl ester

Supplier: Cayman Chemical

Estrone

Supplier: Cayman Chemical

7-Bromoisoquinoline

Supplier: Cayman Chemical

(S)-17-HDoHE

Supplier: Cayman Chemical

Anti-HMGB1 Mouse Monoclonal Antibody [clone: IMG19N12A1]

Supplier: Cayman Chemical

Anti-JMJD2D Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-PCSK9 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Aprotinin