7802 Results for: "Bioworld Technology"

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The hyaluronan-binding protein 2 (HABP2), also designated plasma hyaluronan-binding protein (PHBP) or factor VII-activating protease , belongs to the peptidase S1 family and contains three EGF-like domains, one kringle domain and one peptidase S1 dom 1 * 100 µG

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H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin sw 1 * 100 µG

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Inhibitor of apoptosis proteins (IAPs) contain conserved, unique aminoterminal baculovirus IAP repeats (BIRs) and usually a C-termin al RING finger domain. 1 * 100 µG

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Olfactory receptors are G protein-coupled receptor proteins that localize to the cilia of olfactory sensory neurons where they displ ay affinity for and bind to a variety of odor molecules. 1 * 100 µG

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Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochond rial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic aci 1 * 100 µG

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Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal pro teins for destruction. 1 * 100 µG

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This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins. 1 * 100 µG

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Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled fr om classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or 1 * 100 µG

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Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific targe t cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens 1 * 100 µG

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The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gr adient across the inner mitochondrial membrane, ultimately resulting in the production of water. 1 * 100 µG

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Natural killer (NK) and T cells express a superfamily of proteins with structural features of C-type lectins. T cells bearing natura l killer receptors (NKRs) such as CD94 and CD161 are present in psoriasis. 1 * 100 µG

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Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. 1 * 100 µG

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The E2F transcription factors are essential for regulation of the cell cycle. Physiological E2F is a heterodimer composed of an E2F subunit together with a DP subunit. 1 * 100 µG

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BCAP29 polyclonal antibody detects endogenous levels of BCAP29 protein 1 * 100 µG

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PENK polyclonal antibody detects endogenous levels of PENK protein 1 * 100 µG

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Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and li kely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motif 1 * 100 µG

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NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membr ane. 1 * 100 µG

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NRG4(neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. 1 * 100 µG

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The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. 1 * 100 µG

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This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paire d box domain, an octapeptide, and a paired-type homeodomain. T 1 * 100 µG

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ACAT-1 (acetyl-Coenzyme A acetyltransferase 1) is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. 1 * 100 µG

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Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H 1 methyltransferase activity 1 * 100 µG

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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. 1 * 100 µG

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NDUFB1 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1), also known as CI-MNLL (complex I-MNLL), CI-SGDH or NADH-ubiqui none oxidoreductase MNLL subunit, is a 58 amino acid single-pass membrane protein that localizes to the matrix side o 1 * 100 µG

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ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response and appear to be abundant in certain tumors. 1 * 100 µG

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Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells (By similarity) 1 * 100 µG

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SPT4 (also designated Suppressor of Ty4 and p14) and SPT5 (also designated DSIF p160) are highly conserved proteins from yeast to hu mans. Nuclear SPT4 and SPT5 are involved in both DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole)-mediated tran 1 * 100 µG

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The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. 1 * 100 µG

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ASF1 was first identified in S. cerevisiae based on its ability to de-repress transcriptional silencing when overexpressed . While o nly one gene exists in yeast and Drosophila, mammalian cells contain the two highly homologous ASF1A and ASF1B genes 1 * 100 µG

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Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodime rize to produce more than 20 different receptors. 1 * 100 µG