154 Results for: "1,1-Diphenylethylene oxide&amp"

Supplier: Apollo Scientific

1,1-Diphenylethylene oxide 97%

Supplier: Thermo Fisher Scientific

Appearance: White Crystalline powder or crystals

Supplier: Abcam

PE Mouse monoclonal [11] to Oxidative Stress Defense.

Supplier: Thermo Fisher Scientific

Yttrium ≥99% (REO, rare earth oxide basis), ingot/button, Ø 50.8 mm (2.0 in), Thickness: 11 mm (0.43 in)

Supplier: Novabiochem (Part of Merck)

Iodine 0.02 M in THF : pyridine : water (69:22:11) (w:w:w), Novabiochem® for DNA/RNA synthesis, oxidizing reagent B

Supplier: Merck

It contains <1.0% oleic acid stabilizing ligands.

Supplier: Thermo Fisher Scientific

Pure Al₂O₃ Aluminium oxide AL23.

Supplier: Apollo Scientific

[1,1'-binaphthalene]-2,2'-diylbis(diphenylphosphine oxide) 25g pack 1 * 25 g

Supplier: Apollo Scientific

Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide 1g pack 1 * 1 g

Supplier: Apollo Scientific

Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide 5g pack 1 * 5 g

Supplier: Apollo Scientific

Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide 25g pack 1 * 25 g

Supplier: SIGMA ALDRICH MICROSCOPY

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is also called as Dil. It can be used to study HCV (Hepatitis C virus) cell interactions in the HCV entry process. It is used to label oxidized LDL (low-density lipoprotein) to quantify the uptake of DiI-oxLDL in human endothelial cells.

Supplier: USP

Desloratadine N-oxide (25 mg) (8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 1-Oxide) 1 * 25 mg

Supplier: Apollo Scientific

(11Br)-2,6-Di([1,1’-Biphenyl]-4-Yl)-4-Hydroxydinaphtho[2,1-D:1’,2’-F][1,3,2]Dioxaphosphepine 4-Oxide 1g pack 1 * 1 g

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1’-biphenyl]-4-yl)-4-hydroxydinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-oxide 1g pack 1 * 1 g

Supplier: MP Biomedicals

1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1’-biphenyl]-4-yl)-4-hydroxydinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-oxide 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

(11Br)-2,6-Di([1,1’-Biphenyl]-4-Yl)-4-Hydroxydinaphtho[2,1-D:1’,2’-F][1,3,2]Dioxaphosphepine 4-Oxide 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1’-biphenyl]-4-yl)-4-hydroxydinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-oxide 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

(11Br)-2,6-Di([1,1’-Biphenyl]-4-Yl)-4-Hydroxydinaphtho[2,1-D:1’,2’-F][1,3,2]Dioxaphosphepine 4-Oxide 100mg pack 1 * 100 mg

Supplier: STEMCELL Technologies

Interleukin 11 (IL-11) is a pleiotropic cytokine with effects on various tissues including the bone marrow, brain, and intestinal mucosa (Du and amp; Williams). It belongs to the IL-6 family of cytokines that share a common signal transducer, gp130. Culture of mouse bone marrow cells with IL-11 in combination with IL-3, IL-6, and stem cell factor induces significant expansion and proliferation of colony-forming cells in vitro (Peters et al.). In addition, in combination with IL-3, IL-11 significantly enhances the growth of megakaryocytic colonies in vitro, suggesting its role in augmenting mouse megakaryopoiesis (Yonemura et al.). IL-11 is expressed in a wide range of normal adult mouse tissues, including the central nervous system, thymus, lung, and bone. The mouse IL-11 cDNA was cloned using an expression library generated from the lipopolysaccharide-induced mouse fetal thymic cell line, T2 (Morris et al.). The binding of IL-11 to its receptor induces heterodimerization with the gp130 subunit and activation of JAK tyrosine kinases. IL-11 also plays a role in cancer progression by inducing the proliferation of epithelial cancer cells and the survival of metastatic cells at distant organs. Recently, IL-11 has gained interest for its role in the pathogenesis of diseases in dysregulated mucosal homeostasis associated with STAT3 upregulation, including gastrointestinal cancers (Putoczki et al.).

Supplier: Apollo Scientific

(11bR)-2,6-Bis([1,1-Biphenyl]-4-yl)-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxy-4-Oxide-Dinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepin 1 g pack 1 * 1 g

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1-Biphenyl]-4-yl)-4-Hydroxy-8,9,10,11,12,13,14,15-Octahydrodinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepine 4-Oxide 1g pack 1 * 1 g

Supplier: Apollo Scientific

(11bR)-2,6-Bis([1,1-Biphenyl]-4-yl)-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxy-4-Oxide-Dinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepin 2 50mg pack 1 * 250 mg

Supplier: Apollo Scientific

(11bR)-2,6-Bis([1,1-Biphenyl]-4-yl)-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxy-4-Oxide-Dinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepin 1 00mg pack 1 * 100 mg

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1-Biphenyl]-4-yl)-4-Hydroxy-8,9,10,11,12,13,14,15-Octahydrodinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepine 4-Oxide 25 0mg pack 1 * 250 mg

Supplier: Apollo Scientific

(11bS)-2,6-Di([1,1-Biphenyl]-4-yl)-4-Hydroxy-8,9,10,11,12,13,14,15-Octahydrodinaphtho[2,1-d:1,2-f][1,3,2]Dioxaphosphepine 4-Oxide 10 0mg pack 1 * 100 mg

Supplier: Bioss

H6PD (hexose-6-phosphate dehydrogenase, GDH/6PGL endoplasmic bifunctional protein) is a 789 amino acid protein encoded by the human gene H6PD. The N-terminal section of H6PD belongs to the glucose-6-phosphate dehydrogenase family, while the C-terminal section belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily. H6PD is responsible primarily for the oxidation of glucose-6-phosphate and glucose. It also oxidizes other hexose-6-phosphates. H6PD catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. Reduced nicotinamide adenine dinucleotide phosphate is a necessary cofactor for the reductase activity of 11∫-hydroxysteroid dehydrogenase type 1, which converts hormonally inactive cortisone to active cortisol (in rodents, 11-dehydrocorticosterone to corticosterone).

Supplier: Enzo Life Sciences

Endothelins are vasoactive peptides that exist in three forms (ET-1, ET-2, and ET-3), and function in the maintenance of vascular tone via two identified seven transmembrane-spanning domain-containing G protein-coupled receptors (GPCR), endothelin A (ETA) and endothelin B (ETB). The human ETA receptor is primarily expressed in vascular smooth muscle cells, including those of the heart (also in myocytes), lung, and brain, and its stimulation generally results in vasoconstriction. Activation of ETA receptors can be stimulated by binding of ET-1 and ET-2, but not ET-3. triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Human ETB receptors are primarily expressed in endothelial cells lining the vessel walls of the lungs, heart, and brain, and in contrast to ETA receptors, stimulation generally results in transient vasodilation. Activation of ETB receptors can be stimulated by binding of all three endothelins, triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Both ETA and ETB receptors signal primarily via coupling to Gq/11 alpha subunits, although Gi/o and Gs coupling are also established mechanisms of endothelin signaling, resulting in stimulation of phospholipases C, A2, and D.

Supplier: ProSci Inc.

AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyses the conversion of aldehydes and ketones to alcohols. It catalyses the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.