Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate) JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2]. 1 * 5 mg
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